Deubiquitinating enzyme USP30 negatively regulates mitophagy and accelerates myocardial cell senescence through antagonism of Parkin

Abstract Cell senescence is associated with age-related Crystal chandelier cleaner pathological changes.Increasing evidence has revealed that mitophagy can selectively remove dysfunctional mitochondria.Overexpression of ubiquitin-specific protease 30 (USP30) has been documented to influence mitophagy and deubiquitination of mitochondrial Parkin sub

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Problematic issues of qualifying actions encroaching upon persons executing justice or preliminary investigation

A prerequisite for this research is a high public hazard of violent crimes committed against persons executing justice or preliminary investigation since this shakes the foundation of justice and buttress of state power P-5-P in general.This suggests the need to research the prevention of such crimes using criminal legal methods.The primary goal of

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